Hepatotoxicity now represents the leading cause of acute liver failure, and is the most common reason for withdrawal of an approved medication. Drug-induced liver injury accounts for over one-half of the acute liver failure cases in the United States.

NIH Action Plan for
Liver Disease Research

 



Products > ThioGel-L


ThioGel - L
Triple Antioxidant Liver Formula

Solubilized Alpha Lipoic Acid - 200 mg Silymarin - 200 mg
Selenium - 70 mcg

 

Regular Retail Price $49.95

Unique formula with complementary biological activities for use in liver dysfunction.




Solubilized Alpha Lipoic Acid
ThioGel products are formulated with a unique and proprietary blend of solubilizing excipients and packaged in softgel capsules.

ThioGel brand products contain the "gold standard" of alpha lipoic acid raw materials that are sourced only from Europe.




Enhanced Bioavailability
It is well known in formulation science that liquid formulations are more readily absorbed and provide higher active substance blood levels. The superior bioavailability of solubilized alpha lipoic acid has been proven in company sponsored animal and human studies.



Triple Antioxidant Liver Formula

The triple antioxidant formula provides a greater level of protection of liver function due to a combined antioxidant effect, that is coupled with a broader range of biological activity. A clinical study performed by Dr. Burton Berkson found that the triple antioxidant approach was effective in treating patients with Hepatitis C, as evidenced by their clinical recovery and remarkably improved laboratory values.


Alpha lipoic Acid (ALA)
is unique among anti-oxidants, demonstrating anti-oxidant activity in aqueous, as well as in lipophilic regions, and in extracellular and intracellular environments. Also unique among anti-oxidants, ALA participates in the recycling of other important endogenous anti-oxidants such as vitamins E and C, ubiquinone and glutathione. An abundance of evidence exists that diabetic complications, renal failure, viral infections and other disorders are linked to excess levels of free radicals and the damage they cause to DNA, lipid membranes, and enzyme systems.

Silymarin (Milk Thistle) alters the outer liver membrane cell structure in such a way that certain toxins, as demonstrated with the toxins of the Deathcap mushroom, cannot enter the cell. Silymarin also stimulates RNA polymerase A (also known as polymerase I), enhancing ribosome protein synthesis, resulting in activating the regenerative capacity of the liver through cell development. Silymarin has been shown to possess potent anti-cancer effects, and has been used clinically to treat toxic hepatitis, fatty liver, cirrhosis, ischemic injury, radiation toxicity, and viral hepatitis. Silymarin also works as an antioxidant by scavenging free radicals and inhibiting lipid peroxidation.

Selenium is a powerful antioxidant molecule, and has the added benefit of increasing the activity of glutathione peroxidase. There is a great deal of evidence indicating that selenium supplementation at high levels reduces the incidence of cancer in animals.

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.